Expertise:
Neuroanatomy,
intracellular physiology, realistic models of neural structures
Research in the Ulinski laboratory is concerned with understanding
how neurons in the visual cortex interact to produce behaviors.
We work with an in vitro preparation of the eye and brain
of freshwater turtles. This preparation allows us to present
visual stimuli to the eye and study the responses of the
visual cortex using a variety of methods. The work is part
of a collaborative effort that includes Bijoy Ghosh in Electrical
and Systems Engineering at Washington University, David Senseman
in Biology at the University of Texas at San Antonio and
Kay Robbins in Computer Science at the University of Texas
at San Antonio. Contributions in the Ulinski laboratory include
using neuroanatomical techniques to characterize the structure
of the visual cortex, dorsal lateral geniculate complex and
optic tectum of turtles; intracellular physiological techniques
to characterize the biophysical and physiological characteristics
of neurons in these structures; and large-scale simulation
methods to characterize the dynamics of the structures.
Specific research projects:
-- Models of turtle retinal ganglion cells
-- Physiology of neurons in turtle dorsal lateral geniculate
complex
-- Applications of dynamical systems to visual cortex
Laboratory personnel:
None
Recent publications:
Mancilla JG, Ulinski PS. Role of GABAA-mediated
inhibition in controlling the responses of regular spiking
cells in turtle visual cortex. Visual Neurosci. 18: 9 - 24,
2001.
Nenadic Z, Ghosh B, Ulinski PS Modelling and estimation
problems in turtle visual cortex. IEEE Trans. Biomed. Eng.
49: 753 - 762, 2002.
Nenadic Z, Ghosh B, Ulinski PS Propagating waves in visual
cortex: A large-scale model of turtle visual cortex. J. Comput.
Neurosci. 14: 161 - 184, 2003.
Colombe JB, Sylvester J, Block J, Ulinski PS Subpial and
stellate cells: Two populations of interneurons in turtle
visual cortex. J. Comp. Neurol. 47: 333 - 351.
Du X, Ghosh B, Ulinski P Encoding and decoding with spatio-temporal
waves in the turtle visual cortex: Effect of temporal sampling
and noise. IEEE Trans. Biomed. Eng. 52: 566 - 577.
Wang W, Campaigne C, Ghosh B, Ulinski PS Two cortical circuits
control propagating waves in visual cortex. J. Comput. Neurosci.
in press. |
