Expertise:
Biomedical
imaging, imaging physics and mathematics, tomographic image
reconstruction, theoretical image science
Research in the Anastasio laboratory stems primarily from
a project of mine that involves the development and investigation
of a novel imaging modality for brain imaging. Thermoacoustic
tomography (TAT) is an emerging imaging technique with great
potential for a wide range of biomedical imaging applications.
In TAT, a short electromagnetic pulse is used to irradiate
a biological tissue. When the electromagnetic pulse is absorbed
by the tissue, a thermoacoustic effect results in the emission
of acoustic signals that are measured subsequently. The objective
of TAT is to produce an image that represents a map of the
spatially variant electromagnetic absorption properties of
the tissue. Although TAT is being investigated for a variety
of applications, the development of TAT for brain imaging
remains largely unexplored. Microwave-based TAT holds great
promise for both anatomic and functional brain imaging in
primates. However, advancements are needed in both the reconstruction
theory and design of experimental systems. We are collaborating
with a leading group at Texas A&M University in pursuing
these objectives, and are currently preparing a NIH grant
on this topic.
Specific research projects:
-- Development of imaging algorithms for thermoacoustic
tomography brain imaging
-- Development of X-ray phase-contrast imaging methods
-- Development of optical diffraction tomography
-- Development of imaging methods for radiation therapy
applications
Laboratory personnel:
Daxin Shi
shidaxi@iit.edu
Jin Zhang
zhangjin1980@hotmail.com
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